PBK-IN-9
Based on 1 Customer Validation
PBK-IN-9 is a potent PDZ-binding kinase (PBK) inhibitor with an IC50 of 0.64 nM. PBK-IN-9 can be used for research on breast cancer, lung cancer, bladder cancer and prostate cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.45%
- CAS. Nr.: 1338540-55-8
- Formel: C20H18N2O2S
- Molecular Weight:350.43
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
PBK-IN-9 (Compound 1160) (72 h) inhibits the proliferation of BT549, T47D, A549, HT1197, and 22Rv1 cells, with IC50 values of 54, 57, 56, 230, and 69 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1338540-55-8
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Appearance Solid
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Molecular Weight 350.43
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Formel C20H18N2O2S
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Color Off-white to light yellow
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SMILES
O=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2)C4=C1SC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 10 mg/mL (28.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8536 mL | 14.2682 mL | 28.5364 mL | 71.3409 mL |
| 5 mM | 0.5707 mL | 2.8536 mL | 5.7073 mL | 14.2682 mL | |
| 10 mM | 0.2854 mL | 1.4268 mL | 2.8536 mL | 7.1341 mL | |
| 15 mM | 0.1902 mL | 0.9512 mL | 1.9024 mL | 4.7561 mL | |
| 20 mM | 0.1427 mL | 0.7134 mL | 1.4268 mL | 3.5670 mL | |
| 25 mM | 0.1141 mL | 0.5707 mL | 1.1415 mL | 2.8536 mL |