Pirsidomine
Pirsidomine is a nitric oxide donor. Pirsidomine is a sydnonimine compound. Pirsidomine can transform into a nitric oxide-releasing metabolite in vivo. Pirsidomine prevents occlusion-induced increase in flow in the non-occluded circumflex coronary artery and significantly reduces the blood flow in non-ischemic areas in myocardial infarction dog model. Pirsidomine can be studied in research on cardiovascular diseases.
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- CAS. Nr.: 132722-74-8
- Formel: C17H22N4O3
- Molecular Weight:330.38
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 132722-74-8
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Molecular Weight 330.38
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Formel C17H22N4O3
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SMILES
C[C@H]1N([N+]2=NOC([N-]C(C3=CC=C(OC)C=C3)=O)=C2)[C@H](CCC1)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Martorana, P. A., et al., (1994). Antiischemic effects of pirsidomine, a new nitric oxide donor. European journal of pharmacology, 257(3), 267-273. [Content Brief]
[2]. Stengele, E., et al., (1996). Short-term hemodynamic, anti-ischemic, and antianginal effects of pirsidomine, a new sydnonimine. The American journal of cardiology, 77(11), 937-941. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)