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Art. -Nr.: HY-143474

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POP-IN-3

Y-29794 (Compound 2) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a K_i of 0.95 nM. Y-29794 can be used for studying neurodegenerative diseases and cancer.

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CAS. Nr.: 2554621-98-4
Formel: C₂₂H₃₂N₂OS₂
Molecular Weight:404.63

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

POP-IN-3 Chemical Structure

CAS. Nr.: 2554621-98-4

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Preis

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Y-29794 (Compound 2) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a K_i of 0.95 nM. Y-29794 can be used for studying neurodegenerative diseases and cancer^[1].

IC₅₀ & Target

IC₅₀: 0.95 nM (POP)^[1]

Chemical Information

CAS. Nr. 2554621-98-4
Molecular Weight 404.63
Formel C₂₂H₃₂N₂OS₂
SMILES

O=C(C1=CC=C(C(C)C)N=C1SCCCCCCCN(C)C)C2=CC=CS2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Jessica Plescia, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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