PASK
PASK, PAS domain-containing kinase, is an AMPK-related kinase whose amino-terminal PAS modules belong to a family of sensing domains that in other proteins bind oxygen, heme, and small metabolites, suggesting nutrient-sensing capacity. PASK is expressed in pancreatic beta cells, where mouse studies support roles in beta-cell proliferation and insulin secretion, and its fungal orthologs Psk1 and Psk2 regulate sugar metabolism and translation. In mammals PASK has been implicated in cellular responses to nutrient and oxygen availability, including reported modulation of mechanistic target of rapamycin complex 1 signaling through phosphorylation of the scaffold Raptor. These findings position PASK as a candidate integrator of environmental cues with metabolic and growth control.
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PASK Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
