Przewaquinone B
Przewaquinone B is an abietane-type diterpene quinone (tanshinone) and a diterpenoid compound. Przewaquinone B can be isolated from the rhizomes of Salvia miltiorrhiza Bunge, the roots of Salvia przewarskii, and the roots of Salvia constanea. Przewaquinone B exhibits antitumor activity against cervical cancer and promyelocytic leukemia. Przewaquinone B can be used in research related to cervical cancer and promyelocytic leukemia.
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- CAS. Nr.: 76829-01-1
- Formel: C18H12O4
- Molecular Weight:292.29
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
19.0 μM
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Cytotoxicity against human cervical cancer HeLa cells.
Cytotoxicity against human cervical cancer HeLa cells.
|
27032190 |
| HL-60 | IC50 |
3.0 μM
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Cytotoxicity against human promyelocytic leukemia HL-60 cells.
Cytotoxicity against human promyelocytic leukemia HL-60 cells.
|
27032190 |
Przewaquinone B exhibits weak cytotoxicity against HeLa cells (IC50 = 19.0 μM) and significant cytotoxicity against HL-60 cells (IC50 = 3.0 μM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 76829-01-1
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Molecular Weight 292.29
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Formel C18H12O4
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SMILES
O=C1C(C2=C(C3=C1C(C=CC=C4C)=C4C=C3)OC=C2CO)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)