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Art. -Nr.: HY-106083

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Quazolast

(Synonyms: RHC 3988)

Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers.

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CAS. Nr.: 86048-40-0
Formel: C₁₂H₇ClN₂O₃
Molecular Weight:262.65

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Quazolast Chemical Structure

CAS. Nr.: 86048-40-0

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Biologische Aktivität
- Beschreibung
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vivo

Quazolast (0.2, 1, 5 mg/kg; p.o.) reduces the gastric damage in rats induced by absolute ethanol (0.9 mg/kg)^[1].
Quazolast (3.1, 6.3, 12.5, 25 mg/kg; p.o.) reduces the gastric damage associated with 0.6 N HC1 administration^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

150 g Male Sprague Dawley rat^[1]
Dosage:

0.2, 1, 5 mg/kg
Administration:

P.o.
Result:

Decreased the rat gastric mucosa damage in a dose dependent manner and reduced the gastric ulcer index (68%) at 5 mg/kg in rat induced by absolute ethanol (0.9 mg/kg).

Chemical Information

CAS. Nr. 86048-40-0
Molecular Weight 262.65
Formel C₁₂H₇ClN₂O₃
SMILES

COC(C1=NC2=CC(Cl)=C3C(N=CC=C3)=C2O1)=O
Synonyms

RHC 3988
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Fitzpatrick LR, et al. Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats. Agents Actions. 1991 Jul;33(3-4):330-6. [Content Brief]

[2]. Dave NK, et al. A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen. Ann Allergy. 1990 Oct;65(4):298-302. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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