RI-OR2
RI-OR2, a retro-inverso peptide, is an amyloid-β (Aβ) oligomerization inhibitor. RI-OR2 binds to immobilized β-Amyloid (1-42) (HY-P1363A) monomers and fibrils, with an apparent Kd of 9-12 μM, and also acted as an inhibitor of Aβ(1-42) fibril extension.
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- CAS. Nr.: 1219627-58-3
- Formel: C53H85N17O10
- Molecular Weight:1120.35
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
In Vitro
RI-OR2 significantly reverses the toxicity of Aβ(1-42) toward cultured SH-SY5Y neuroblastoma cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1219627-58-3
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Molecular Weight 1120.35
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Formel C53H85N17O10
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Sequence
Ac-{d-Arg}-Gly-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-Gly-{d-Arg}-NH2
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Sequence Shortening
Ac-{d-Arg}-G-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-G-{d-Arg}-NH2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
RI-OR2 Related Classifications
HY-P10823 Related Classifications
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