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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
RACK
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "RACK" in MCE Product Catalog:
2
2 Cited Publications
Art. -Nr.: HY-N10335
CAS. Nr.: 64761-48-4
Category:
Cephalotaxaceae Extract Ketones, Aldehydes, Acids Cephalotaxus harringtonia Plants Disease Research Fields Inflammation/Immunology Cancer
Target:
Target:
Forschungsgebiete:
M435-1279 is a UBE2T inhibitor. M435-1279 inhibits the Wnt/β-catenin signaling pathway hyperactivation through blocking UBE2T-mediated degradation of RACK1 .
Art. -Nr.: HY-E0225
The 0.5 mL SBS Rack is a 96-well biobank storage rack suitable for -80°C environments. It can hold 0.5 mL externally threaded cryogenic vials with 2D codes on the bottom, and supports automated sample tracking, detection, and laboratory information system integration. The 0.5 mL SBS Rack can be used with camera-based reading devices to scan and log biobank vials with 2D codes into databases, enabling rapid identification of aliquoted samples .
Art. -Nr.: HY-RS11595
Target:
Forschungsgebiete:
RACK1 Human Pre-designed siRNA Set A contains three designed siRNAs for RACK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-162254
CAS. Nr.: 3032642-29-5
EGFR T790M/L858R/ACK1-IN-1 is a dual inhibitor of EGFR T790M/L858R and ACK1. IC50 values are 23 and 263 nM, respectively. EGFR T790M/L858R/ACK1-IN-1 can inhibit cell proliferation and has antitumor activity .
Art. -Nr.: HY-174975
Target:
Forschungsgebiete:
JY-21 is a BRD4 PROTAC degrader active against both long and short BRD4 isoforms. JY-21 binds to TRIM28, RACK1, LMO7 and FUS to induce proteasomal degradation of BRD4 isoforms (DC50: 5.944 μM for long BRD4 isoform; 3.797 μM for short BRD4 isoform). JY-21 is applicable to research related to triple-negative breast cancer .
Art. -Nr.: HY-P1371
Synonyms: KKWKMRRNQFWIKIQRC CSVEIWD*
Art. -Nr.: HY-RS23221
Target:
Forschungsgebiete:
Rack1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rack1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-P3879
CAS. Nr.: 149839-94-1
Synonyms: PKC βII (660-673)
Art. -Nr.: HY-115907A
CAS. Nr.: 2915618-92-5
Target:
Forschungsgebiete:
(rac)-K20 is the racemate of K20, a KRas G12C inhibitor with an IC50 of 1.16 μM. K20 has antitumor activity .
Art. -Nr.: HY-E0225
compounds
0.5 mL 96-Well Tube Rack, compliant with the industry-standard SBS (Society for Biomolecular Screening) specifications. This product features a sliding lock mechanism on the lid to prevent tube dislodgement. The side of the rack is equipped with an identifiable barcode for easy compound storage and retrieval. The matching tube (HY-E0224) is made from the same material as this tube, effectively preventing uneven expansion issues during freeze-thaw cycles.
Art. -Nr.: HY-174994
Target:
Forschungsgebiete:
JY-5 is an E3 ligase ligand that can bind to TRIM28, RACK1, LMO7 and FUS. JY-5 can be used for synthesis of PROTAC JY-21 (HY-174975) .
Art. -Nr.: HY-P0221B
Target:
Forschungsgebiete:
Art. -Nr.: HY-RS16781
Target:
Forschungsgebiete:
Rack1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rack1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-P74606
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RACK1; Receptor Of Activated Protein C Kinase 1; Prev. GNB2L1; HLC-7; Small Ribosomal Subunit Protein RACK1; Protein Homologous To Chicken B Complex Protein, Guanine Nucleotide Binding; Gnb2-Rs1; Guanine Nucleotide Binding Protein Beta Polypeptide 2-Like
Species:
Human
Source:
E. coli
Art. -Nr.: HY-181165
CAS. Nr.: 3111225-79-4
SB2960 is a receptor for activated protein C kinase 1 (RACK1) binder with a human KD of 5.65 μM. SB2960 can promote stress granule (SG) formation and exhibit potent antiviral activity across diverse viral species. SB2960 suppresses viral replication with minimal cytotoxicity by modulating host antiviral immune responses. SB2960 increases the thermal stability of RACK1 and reduces SARS-CoV-2 N protein levels. SB2960 enhances type I interferon (IFN-β) expression and inhibits RIG-I, ISG56, and RANTES expression. SB2960 can be used for the research of virus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
