JY-21
JY-21 is a BRD4 PROTAC degrader with a DC50 of 3.797 μM. JY-21 has a potent anticancer activity against MDA-MB-231 cells. Pink: BRD4 ligand (HY-78695); Blue: E3 ligase ligand (HY-174994); Black: linker (HY-151862)
(Pink: BRD4 ligand (HY-78695); Blue: Ligands for E3 Ligase ligand (HY-174994); Black: linker (HY-151862)).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C42H50ClN11O4SSi
- Molecular Weight:868.52
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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BRD4 3.797 μM (DC50) |
Chemical Information
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Molecular Weight 868.52
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Formel C42H50ClN11O4SSi
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SMILES
CC1=C(C(C(C2=CC=C(C=C2)Cl)=N[C@H]3CC(NCCCN4C=C(N=N4)COC5=CC=C(C([N+]([O-])=O)=C5)/N=N/C#C[Si](C(C)C)(C(C)C)C(C)C)=O)=C(N6C3=NN=C6C)S1)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)