SHR5133
SHR5133 is a highly potent, orally active HBV capsid assembly modulator. SHR5133 displays HBV DNA reduction (EC50=26.6 nM).
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- CAS. Nr.: 2270943-23-0
- Formel: C19H18F4N6O2
- Molecular Weight:438.38
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
>100 μM
Compound: 22; SHR5133
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Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer-glo assay
Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer-glo assay
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[PMID: 35300087] |
Chemical Information
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CAS. Nr. 2270943-23-0
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Molecular Weight 438.38
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Formel C19H18F4N6O2
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SMILES
O=C(C1=C2CN(C(NC3=CC=C(F)C(C#N)=C3)=O)[C@@H](C)CN2C=N1)N[C@H](C)C(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SHR5133 Related Classifications
HY-144319 Related Classifications
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