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Art. -Nr.: HY-148645

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STING modulator-4

STING modulator-4 (compound AIH05) is a competitive STING modulator with a K_i of 0.0933 μM for R232H STING. STING modulator-4 has an EC₅₀ of >10 μM for p-IRF3 in THP-1 cell.

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CAS. Nr.: 2839639-72-2
Formel: C₁₇H₁₈N₈O
Molecular Weight:350.38

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

STING modulator-4 Chemical Structure

CAS. Nr.: 2839639-72-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

STING modulator-4 (compound AIH05) is a competitive STING modulator with a K_i of 0.0933 μM for R232H STING. STING modulator-4 has an EC₅₀ of >10 μM for p-IRF3 in THP-1 cell^[1].

Chemical Information

CAS. Nr. 2839639-72-2
Molecular Weight 350.38
Formel C₁₇H₁₈N₈O
SMILES

O=C(C1=CC2=C(C=NN2C)C(C3=NC(C4=CC=NN4CC)=CN3C)=N1)N
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ketan Satish GAJIWALA, et al. Modulators of sting (stimulator of interferon genes). WO2022195462A1.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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