T-1032
T-1032 is a selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 value of 1.0 nM. T-1032 shows relaxant effect on isolated rabbit corpus cavernosum. T-1032 can be used for the research of erectile dysfunction.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 212500-03-3
- Formel: C32H31N3O11S
- Molecular Weight:665.67
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
PDE5 1.0 nM (IC50) |
In Vitro
T-1032 (Compound 63) shows relaxant effect on isolated rabbit corpus cavernosum with an EC30 of 7.9 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS. Nr. 212500-03-3
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Molecular Weight 665.67
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Formel C32H31N3O11S
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SMILES
OS(O)(=O)=O.NC1=CC=C(N2C(C(OC)=O)=C(C3=CC(OC)=C(C(OC)=C3)OC)C4=C(C=C(C=C4)OCC5=NC=CC=C5)C2=O)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
T-1032 Related Classifications
HY-W705784A Related Classifications
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