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Art. -Nr.: HY-111766

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YD-3

YD-3 is a platelet activation inhibitor. YD-3 inhibits Thrombine-induced rabbit platelets aggregation (IC₅₀: 28.3 μM) and phosphoinositol production. In addition, YD-3 also inhibits Trypsin-induced platelet aggregation in human and rabbit with the IC₅₀ of 38.1 μM and 5.7 μM, respectively, but does not affect the proteolytic activity of trypsin.

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CAS. Nr.: 170632-41-4
Formel: C₂₃H₂₀N₂O₂
Molecular Weight:356.42

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

YD-3 Chemical Structure

CAS. Nr.: 170632-41-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
Platelet	IC₅₀	>10 μM Compound: YD-3	Inhibition of collagen-induced human platelet aggregation Inhibition of collagen-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	>10 μM Compound: YD-3	Inhibition of SFLLRN-induced human platelet aggregation Inhibition of SFLLRN-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	>10 μM Compound: YD-3	Inhibition of thrombin-induced human platelet aggregation Inhibition of thrombin-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	>10 μM Compound: YD-3	Inhibition of U46619-induced human platelet aggregation Inhibition of U46619-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	0.13 μM Compound: YD-3	Inhibition of GYPGKF-induced human platelet aggregation Inhibition of GYPGKF-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	164 μM Compound: 11	Inhibition of PAF-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by PAF addition Inhibition of PAF-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by PAF addition	[PMID: 33049608]
Platelet	IC₅₀	184.8 μM Compound: 11	Inhibition of arachidonic acid-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by arachidonic acid addition Inhibition of arachidonic acid-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by arachidonic acid addition	[PMID: 33049608]
Platelet	IC₅₀	212.4 μM Compound: 11	Inhibition of collagen-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by collagen addition Inhibition of collagen-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by collagen addition	[PMID: 33049608]
Platelet	IC₅₀	29.3 μM Compound: 11	Inhibition of thrombin-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by thrombin addition Inhibition of thrombin-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by thrombin addition	[PMID: 33049608]

Chemical Information

CAS. Nr. 170632-41-4
Molecular Weight 356.42
Formel C₂₃H₂₀N₂O₂
SMILES

O=C(OCC)C1=CC=C(C2=NN(CC3=CC=CC=C3)C4=C2C=CC=C4)C=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Zhang Z, et al. Short day promotes gall swelling by a CONSTANS-FLOWERING LOCUS T pathway in Zizania latifolia. Plant J. 2024 Nov;120(3):1014-1031. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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