Anticancer agent 88
Anticancer agent 88 is a spirooxindole-furan derivative with anticancer activity. Anticancer agent 88 can be used for the research of breast adenocarcinoma and human liver cancer.
For research use only. We do not sell to patients.
- Formula: C35H29BrCl2N2O3
- Molecular Weight:676.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Anticancer agent 88 (Compound 6d) potently inhibits the viability of MCF7 human breast adenocarcinoma cells with an IC50 of 4.3 μM/mL[1].
Anticancer agent 88 inhibits the viability of HepG2 human liver carcinoma cells with an IC50 of 6.9 μM/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 676.43
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Formula C35H29BrCl2N2O3
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SMILES
O=C1NC2=C(C=CC(Cl)=C2)[C@@]13N4C([C@@H](C5=CC=C(C6=CC=C(Cl)C=C6)O5)[C@@H]3C(C7=CC=C(Br)C=C7)=O)CC8CCCCC48
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)