Colchicine (Standard)
Based on 1 Customer Validation
Colchicine (Standard) is the analytical standard of Colchicine. This product is intended for research and analytical applications. Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research.
For research use only. We do not sell to patients.
- Purity : 99.93%
- CAS No.: 64-86-8
- Formula: C22H25NO6
- Molecular Weight:399.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 64-86-8
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Appearance Solid
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Molecular Weight 399.44
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Formula C22H25NO6
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Color White to light yellow
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SMILES
CC(N[C@H](C1=C2)CCC3=CC(OC)=C(OC)C(OC)=C3C1=CC=C(OC)C2=O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (643 KB)
- English - EN (643 KB)
- Français - FR (643 KB)
- Deutsch - DE (643 KB)
- Norwegian - NO (643 KB)
- Español - ES (643 KB)
- Swedish - SV (643 KB)
- Italian - IT (643 KB)
- Korean - KR (643 KB)
- Portuguese - PT (643 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Colchicine (Standard)
- 64-86-8
- Reference Standards
- Microtubule/Tubulin
- NOD-like Receptor (NLR)
- Autophagy
- Apoptosis
- Orally
- alkaloid
- tubulin
- microtubule
- α3 glycine receptors
- GlyRs
- non-steroidal anti-inflammatory drug
- NSAID
- intestinal injury
- immunosuppressive
- anti-fibrosis
- gouty arthritis
- Alzheimer’s disease
- AD
- Inhibitor
- inhibitor
- inhibit