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Cat. No.: HY-N0359A

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(E)-Cynarin

(Synonyms: (E)-Cynarine; (E)-Plemocil)

(E)-Cynarin ((E)-Cynarine) is the E-isomer of Cynarin (HY-N0359). Cynarin is an anti-asphyxiant with multiple biological activities, possessing antioxidant, antihistamine, and antiviral activities, etc.

For research use only. We do not sell to patients.

CAS No.: 212891-05-9
Formula: C₂₅H₂₄O₁₂
Molecular Weight:516.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

(E)-Cynarin Chemical Structure

CAS No.: 212891-05-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	ED₅₀	4 μM Compound: 1,5-DCQA	Concentration that inhibits Human Immunodeficiency Virus Type 1 (HIV-1)-induced death of MT-2 cells Concentration that inhibits Human Immunodeficiency Virus Type 1 (HIV-1)-induced death of MT-2 cells	[PMID: 9986720]

Chemical Information

CAS No. 212891-05-9
Molecular Weight 516.45
Formula C₂₅H₂₄O₁₂
SMILES

OC(C=C1/C=C/C(O[C@]2(C[C@H]([C@H]([C@@H](C2)O)O)OC(/C=C/C3=CC(O)=C(C=C3)O)=O)C(O)=O)=O)=C(C=C1)O
Synonyms

(E)-Cynarine; (E)-Plemocil
Structure Classification
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Topal M, et al. Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.). J Enzyme Inhib Med Chem. 2016;31(2):266-75. [Content Brief]

[2]. Dong GC, et al. Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor. Pharm Res. 2009 Feb;26(2):375-81. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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