SD 8381
SD 8381 is a potent and selective COX-2 inhibitor. SD 8381 shows IC50 values of 0.0098 μM for hCOX-2 and 0.69 μM for hCOX-1.
For research use only. We do not sell to patients.
- CAS No.: 215123-80-1
- Formula: C11H5Cl2F3O3
- Molecular Weight:313.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
hCOX-1 0.69 μM (IC50) |
hCOX-2 0.0098 μM (IC50) |
Chemical Information
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CAS No. 215123-80-1
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Molecular Weight 313.06
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Formula C11H5Cl2F3O3
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SMILES
ClC1=C2C(C=C([C@H](O2)C(F)(F)F)C(O)=O)=CC(Cl)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SD 8381 Related Classifications
HY-108019 Related Classifications
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