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Cat. No.: HY-161418

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1-NBX

1-NBX is a potent and selective A₁R ligand. 1-NBX exhibits significantly improved A₁R affinity with with a K_i of 2.6 nM and lower affinity for the A₂A receptor with a K_i of 164 nM.

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Formule: C₁₈H₂₅FN₄O₂
Masse moléculaire:348.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

1-NBX Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

1-NBX is a potent and selective A₁R ligand. 1-NBX exhibits significantly improved A₁R affinity with with a K_i of 2.6 nM and lower affinity for the A₂A receptor with a K_i of 164 nM^[1].

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Chemical Information

Masse moléculaire 348.42
Formule C₁₈H₂₅FN₄O₂
SMILES

O=C1C2=C(N=C([C@]34CC[C@@H](C4)CC3)N2)N(CCCF)C(N1CCC)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Swen Humpert, et al. 8-Bicycloalkyl-CPFPX derivatives as potent and selective tools for in vivo imaging of the A1 adenosine receptor. Eur J Med Chem. 2024 Apr 6:271:116380. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Chemical Information
Pureté et documentation
Références

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1-NBX

Voir tous les produits spécifiques à Isoform Adenosine Receptor

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

1-NBX Related Classifications

HY-161418 Related Classifications

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Keywords

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