2-Hydroxy Ibuprofen
2-Hydroxy Ibuprofen ((±)-2-Hydroxy Ibuprofen) is a major oxidative metabolite of Ibuprofen (HY-78131). 2-Hydroxy Ibuprofen undergoes phase II metabolism, forming a β-1-O-acyl glucuronide conjugate at the carboxyl group of its propionic acid side chain. 2-Hydroxy Ibuprofen can be used for metabolism-related research.
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- CAS No.: 51146-55-5
- Formule: C13H18O3
- Masse moléculaire:222.28
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
2‑Hydroxy Ibuprofen can generate a β‑1‑O‑acyl glucuronide conjugate at the carboxylic acid site of the propionic acid side chain during Phase II metabolism[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 51146-55-5
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Masse moléculaire 222.28
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Formule C13H18O3
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SMILES
O=C(O)C(C)C1=CC=C(CC(C)(O)C)C=C1
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Synonyms
(±)-2-Hydroxy Ibuprofen
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- 2-Hydroxy Ibuprofen
- 51146-55-5
- (±)-2-Hydroxy Ibuprofen
- Drug Metabolite
- Drug Intermediate
- β-1-O-acyl glucuronide conjugate
- propionic acid side chain carboxylic group
- human urine
- phase II metabolism
- ibuprofen metabolite
- isobutyl side chain hydroxylation
- rainbow trout
- activated sludge
- sewage wastewater
- phase I ibuprofen metabolite
- Inhibitor
- inhibitor
- inhibit