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Cat. No.: HY-U00072

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RS-601

Name: RS-601
Brand: MedChemExpress
SKU: HY-U00072
Price: 1347.00 USD
Availability: InStock
Rating: 5 (1 reviews)

RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.

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CAS No.: 207987-59-5
Formule: C₂₂H₂₃F₆NO₄S
Masse moléculaire:511.48

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

RS-601 Chemical Structure

CAS No.: 207987-59-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- In Vivo
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Description

RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.

IC₅₀ & Target^[1]

LTD₄	TXA₂ Receptor

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In Vivo

RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4 in a dose-dependent fashion in guinea pigs. RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction, respectively. RS-601 significantly inhibits the late-phase response and LPS-induced AHR at a dose of 10 mg/kg, but does not affect biphasic bronchial responses. RS-601 (3 and 10 mg/kg) also clearly inhibits the AHR^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 207987-59-5
Masse moléculaire 511.48
Formule C₂₂H₂₃F₆NO₄S
SMILES

O=C(O)CCCC1=CC=C(C(NS(=O)(C2=CC=C(F)C=C2)=O)CCCC(F)(F)C(F)(F)F)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yamada T, et al. Effects of RS-601, a novel leukotriene D(4)/thromboxane A(2) dual receptor antagonist, on asthmatic responses in guinea pigs. Pharmacology. 2003 Sep;69(1):51-8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RS-601

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Montelukast sodium

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LY255283

Masilukast

YM158 free base

SR2640 hydrochloride

ONO4057

Ablukast

Bunaprolast

Etalocib (Standard)

Montelukast sodium (Standard)

Voir tous les produits spécifiques à Isoform Leukotriene Receptor

Voir tous les produits spécifiques à Isoform Prostaglandin Receptor

Activité biologique

Chemical Information

Pureté et documentation

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Help & FAQs

Bioz

RS-601

KP496

Montelukast sodium

Etalocib

LY255283

Masilukast

YM158 free base

SR2640 hydrochloride

ONO4057

Ablukast

Bunaprolast

Etalocib (Standard)

Montelukast sodium (Standard)

Voir tous les produits spécifiques à Isoform Leukotriene Receptor

Voir tous les produits spécifiques à Isoform Prostaglandin Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RS-601 Related Classifications

HY-U00072 Related Classifications

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