ABD459

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ABD459 is a CB1 receptor antagonist with significant effects on regulating food intake and sleep-wake cycles. ABD459 completely displaces CB1 agonist CP99540 (Ki = 8.6 nM) and antagonizes CP55940-induced GTPγS binding (KB = 7.7 nM). ABD459 may specifically modulate endogenous cannabinoid release through cholinergic activity and plays a role in attention and arousal regulation. ABD459 is suitable for research in neurological disorders.

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  • CAS No.: 1047670-51-8
  • Formule: C24H17BrCl2N2O2
  • Masse moléculaire:516.21
  • Stockage:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
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