Adhesamine
Based on 1 publication(s) in Google Scholar
Adhesamine, dumbbell-shaped molecule, activates MAPK/FAK pathway. Adhesamine promotes adhesion and growth of mammalian cells. Adhesamine accelerates the differentiation and improves the survival of mice hippocampal neurons in primary culture.
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- Pureté: 99.46%
- CAS No.: 462605-73-8
- Formule: C24H32Cl4N8O2S2
- Masse moléculaire:670.51
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Adhesamine
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Activité biologique
MAPK/FAK[1]
Adhesamine (20 μg/mL; 0-30 d) facilitates attachment and enhances survival of mouse primary cultured hippocampal neurons. Adhesamine induces neurite branching and rapid differentiation of mouse primary cultured hippocampal neurons[1].
Adhesamine (20 μg/mL; 1 d, 3 d, 4 d) induces cell adhesion by cell-surface heparan sulfate and activates FAK phosphorylation. Adhesamine stimulates neurite differentiation through MAPK activation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 462605-73-8
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Appearance Solid
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Masse moléculaire 670.51
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Formule C24H32Cl4N8O2S2
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Color Off-white to light yellow
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SMILES
O=CC1=C(N=C(SC)N=C1N2CC[N+]3(CC[N+]4(CC3)CCN(CC4)C5=NC(SC)=NC(Cl)=C5C=O)CC2)Cl.[Cl-].[Cl-]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvant et solubilité
DMSO : 1 mg/mL (1.49 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4914 mL | 7.4570 mL | 14.9140 mL | 37.2851 mL |