AK59
Based on 1 Customer Validation
AK59 is a STING degrader that works by leveraging HERC4, a hect domain E3 ligase. AK59 can be used in the study of autoimmune diseases and cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.03%
- Formule: C21H14F3N3O2S
- Masse moléculaire:429.41
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
Chemical Information
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Appearance Solid
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Masse moléculaire 429.41
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Formule C21H14F3N3O2S
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Color Pink to orange
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SMILES
O=S(NC1=C2N=CC=CC2=C(C=C1)C3=CC=CN=C3)(C4=CC=C(C=C4)C(F)(F)F)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 116.67 mg/mL (271.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3288 mL | 11.6439 mL | 23.2878 mL | 58.2194 mL |
| 5 mM | 0.4658 mL | 2.3288 mL | 4.6576 mL | 11.6439 mL | |
| 10 mM | 0.2329 mL | 1.1644 mL | 2.3288 mL | 5.8219 mL | |
| 15 mM | 0.1553 mL | 0.7763 mL | 1.5525 mL | 3.8813 mL | |
| 20 mM | 0.1164 mL | 0.5822 mL | 1.1644 mL | 2.9110 mL | |
| 25 mM | 0.0932 mL | 0.4658 mL | 0.9315 mL | 2.3288 mL | |
| 30 mM | 0.0776 mL | 0.3881 mL | 0.7763 mL | 1.9406 mL | |
| 40 mM | 0.0582 mL | 0.2911 mL | 0.5822 mL | 1.4555 mL | |
| 50 mM | 0.0466 mL | 0.2329 mL | 0.4658 mL | 1.1644 mL | |
| 60 mM | 0.0388 mL | 0.1941 mL | 0.3881 mL | 0.9703 mL | |
| 80 mM | 0.0291 mL | 0.1455 mL | 0.2911 mL | 0.7277 mL | |
| 100 mM | 0.0233 mL | 0.1164 mL | 0.2329 mL | 0.5822 mL |