Copy Link Print Information

AMG-424

(Synonyms: XmAb968)
Avis client

Based on 1 Customer Validation

AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 & CD3E. AMG-424 kills CD38-expressing cancer cells, triggers T-cell proliferation and attenuates cytokine release. AMG 424 has antitumor activity in a bone marrow-invasive mouse cancer model and induces peripheral B-cell depletion in cynomolgus monkeys. AMG-424 can be used in multiple myeloma research. Recommended isotype control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté: 99.32%
  • Masse moléculaire:125.012 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for AMG-424
  • Experimental Validation Results for AMG-424
  • Experimental Validation Results for AMG-424
  • AMG-424 Chemical Structure
    AMG-424 Chemical Structure
Size
Prix
Stock
Quantité
Amount: USD 0.00
Please select quantity
or
or

* Veuillez sélectionner la quantité avant d'ajouter des articles.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
AMG-424 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
  • Activité biologique
  • Chemical Information
  • Pureté et documentation
  • Références
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
100 mg

Obtenir un devis En stock

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Enregistrer
Sign in to MedChemExpress
Enregistrer un nouveau compte

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    half-IGG1-kappa/(scFv-heavy-lambda)-h-CH2-CH3

  • 1/16

    Immobilized Human CD38 Protein, His Tag can bind AMG-424. The EC50 for this effect is 373.8 ng/mL.

  • 1/16

    Immobilized CD3E-His&CD3D without tag can bind AMG-424. The EC50 for this effect is 265.8 ng/mL.

  • AMG-424 Chemical Structure
    1/16
  • AMG-424
  • Immobilized Human CD38 Protein, His Tag can bind AMG-424. The EC50 for this effect is 373.8 ng/mL.
  • Immobilized CD3E-His&CD3D without tag can bind AMG-424. The EC50 for this effect is 265.8 ng/mL.
  • half-IGG1-kappa/(scFv-heavy-lambda)-h-CH2-CH3