country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-183587

Copy Link Print Information

Anticancer agent 322

Anticancer agent 322 is a spirocyclohexane-chroman-4-one derivative. Anticancer agent 322 induces apoptosis and G1 cell cycle arrest in breast cancer cells. Anticancer agent 322 can be used for the research of breast cancer.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₂₄H₂₆ClNO₆
Masse moléculaire:459.92

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Anticancer agent 322 Chemical Structure

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

Anticancer agent 322 (Compound 42) potently inhibits MCF7 breast cancer cell viability with an IC₅₀ of 3.9 μM, while being 9.99-fold and 8.95-fold less cytotoxic to noncancerous MCF10A and VA13 cells, respectively, and moderately cytotoxic to MDAMB231 breast cancer cells^[1].
Anticancer agent 322 (20 μM; 24 h) induces G1-phase cell cycle arrest and slight apoptosis in MCF7 breast cancer cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cycle Analysis^[1]

Cell Line:

MCF7 breast cancer cells
Concentration:

20 μM
Incubation Time:

24 h
Result:

Induced a G1-phase cell cycle arrest in MCF7 cells, as shown by an increased percentage of cells in G1 phase relative to untreated controls.
Observed a slight but notable level of apoptosis in cell death analysis.

Related Protocols :

Chemical Information

Masse moléculaire 459.92
Formule C₂₄H₂₆ClNO₆
SMILES

ClC(C=C1)=CC=C1NC(COC2=CC=C3C(OC4(CCC5(OCCO5)CC4)CC3O)=C2)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ipatova DA, et al. Spirocyclohexane-Chroman-4-one Derivatives as Selectively Cytotoxic Agents in Breast Cancer Models. ACS Med Chem Lett. 2026;17(5):1114-1120. Published 2026 Apr 29. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis