Anticancer agent 94
Anticancer agent 94 is a 4-Hydroxycoumarin derivative. Anticancer agent 94 can inhibit invasion and migration of lung cancer cells by modulating expression of epithelial-mesenchymal transition (EMT) effectors.
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- Formule: C22H15NO4
- Masse moléculaire:357.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Anticancer agent 94 (compound 4i) (5-15 μM; 24 h) significantly inhibits A549 cell invasion by ~ 40%[1].
Anticancer agent 94 (15 μM; 24-72 h) significantly inhibits A549 cell migration[1].
Anticancer agent 94 (5-15 μM; 4 h) inhibits lung cancer cell motility by downregulating EMT markers[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549 cells
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Concentration:5, 10, 15 μM
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Incubation Time:24 hours
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Result:Significantly increased the expression of E-cadherin.
Downregulated the expression of N-cadherin.
Chemical Information
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Masse moléculaire 357.36
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Formule C22H15NO4
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SMILES
O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(C3=O)=C(O)C4=C(O3)C=CC=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 94 Related Classifications
HY-152085 Related Classifications
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