Antitubercular agent-29
Antitubercular agent-29 (compound 6xa) is a potent agent resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 μg/mL against agent-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells.
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- Formule: C20H12ClN3O5
- Masse moléculaire:409.78
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
MIC: 0.03 µg/mL in DS-Mtb, 0.03-0.06 µg/mL in DR-Mtb[1]
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Cell Line
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Type | Value | Description | References |
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| Vero | CC50 |
5 μg/mL
Compound: 6xa
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
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[PMID: 35487101] |
Chemical Information
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Masse moléculaire 409.78
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Formule C20H12ClN3O5
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SMILES
O=C(C1=CC=C(NC2=NC3=CC(Cl)=CC=C3O2)C=C1)/C=C/C4=CC=C([N+]([O-])=O)O4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitubercular agent-29 Related Classifications
HY-150554 Related Classifications
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