Baicalein hydrate

Baicalein hydrate purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Feb:188:106666. [Abstract]

Customer Validation
Intracellular drug release of 80 μg/mL cPBA-BE in HepaRG cells injured by 3 mg/mL APAP (8 h) was observed.

Baicalein hydrate purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Feb:188:106666. [Abstract]

Customer Validation
Representative flow cytometry curves and quantitative data illustrating time-dependent internalization of 10 mg/mL Cy5-labeled cPBA-BE in HepaRG cells until 24 h.

Baicalein hydrate purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Feb:188:106666. [Abstract]

Customer Validation
After mice were injured by 200 mg/kg APAP for 6 h, a single intravenous injection of 100 μL 20 mg/mL cPBA-BE in PBS or 5.1 mg/mL BE in 5% DMSO (equal to 20 mg/mL cPBA-BE) was administered. The expression levels of representative factors of inflammation and oxidative stress in the liver were measured. After 18 h of treatment, homogenates of the hepatic tissues were prepared, and the concentrations of GSH, H2O2, MDA, and MPO were separately measured.

Baicalein hydrate purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2023 Feb:188:106666. [Abstract]

Customer Validation
After mice were injured by 200 mg/kg APAP for 6 h, a single intravenous injection of 100 μL 20 mg/mL cPBA-BE in PBS or 5.1 mg/mL BE in 5% DMSO (equal to 20 mg/mL cPBA-BE) was performed. Masson trichrome (MT) staining of liver sections.

Baicalein hydrate purchased from MedChemExpress. Usage Cited in: Theranostics. 2021 Jul 13;11(17):8301-8321. [Abstract]

Customer Validation
Fluorescence quenching of cPBA after an interaction with various concentrations (0, 3, 6, 12, 24 μg/mL) of BE was observed.