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Cat. No.: HY-119868

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Butaxamine

Name: Butaxamine
Brand: MedChemExpress
SKU: HY-119868
Availability: PreOrder

(Synonyms: Butoxamin)

Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity.

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CAS No.: 2922-20-5
Formule: C₁₅H₂₅NO₃
Masse moléculaire:267.36

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Butaxamine Chemical Structure

CAS No.: 2922-20-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity^[1].

IC₅₀ & Target^[1]

β2 adrenoceptor

Voir tous les produits spécifiques à Isoform Adrenergic Receptor :

In Vivo

Butaxamine (0.1, 1, 10 mg/kg; p.o.; once daily for 12 weeks) increases bone mass indices and biomechanical parameters of strength and toughness in rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Seven-week-old male SHR/Izm and WKY/Izm rats^[1]
Dosage:

0.1, 1, 10 mg/kg
Administration:

P.o.; once daily for 12 weeks
Result:

Prevented a decrease in bone mass and an increase in biomechanical fragility developing in SHR, suppressed both a decrease in bone formation and an increase in bone resorption in SHR.

Chemical Information

CAS No. 2922-20-5
Masse moléculaire 267.36
Formule C₁₅H₂₅NO₃
SMILES

OC(C1=CC(OC)=CC=C1OC)C(C)NC(C)(C)C
Synonyms

Butoxamin
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Arai M, et al. Dose effects of butoxamine, a selective β2-adrenoceptor antagonist, on bone metabolism in spontaneously hypertensive rat. Eur J Pharmacol. 2013 Feb 15;701(1-3):7-13. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références

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Butaxamine

Voir tous les produits spécifiques à Isoform Adrenergic Receptor