Carindacillin
Carindacillin (Indanyl carbenicillin; CP-15464-2 free base) is an orally active prodrug of Carbenicillin (HY-B0525). Carindacillin undergoes intestinal uptake via a proton gradient-driven carrier-mediated pathway and is rapidly hydrolyzed in vivo to release the bioactive Carbenicillin, which interferes with cell wall synthesis by inhibiting bacterial penicillin-binding proteins. Carindacillin can be used in research related to bacterial infections.
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- CAS No.: 35531-88-5
- Formule: C26H26N2O6S
- Masse moléculaire:494.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
Carindacillin (CIPC) is actively transported into rat intestinal BBMV primarily via the monocarboxylic acid transport system, with a Km of 0.54 mM, a Ki of 0.59 mM, and an apparent uptake clearance of 499 × 10-3 µl/mg protein per s[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 35531-88-5
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Masse moléculaire 494.56
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Formule C26H26N2O6S
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SMILES
O=C(OC1=CC=C(CCC2)C2=C1)C(C3=CC=CC=C3)C(N[C@H]4[C@]5([H])N(C4=O)[C@H](C(C)(S5)C)C(O)=O)=O
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Synonyms
Indanyl carbenicillin; CP-15464-2 free base
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Carindacillin
- 35531-88-5
- Indanyl carbenicillin
- CP-15464-2
- Drug Intermediate
- Bacterial
- rat intestinal BBMV
- brush border membrane vesicles
- oligopeptide transporter
- H+-coupled monocarboxylic acid transport system
- Gly-Sar uptake
- carbenicillin
- chronic pyelonephritis
- ceftibuten uptake
- L-lactic acid uptake
- Inhibitor
- inhibitor
- inhibit