1817841-22-7
1817841-22-7
Chemical Structure
MeTC7
- CAS No.: 1817841-22-7
- Formula:C32H48BrN3O4
- Molecular Weight:618.65
IUPAC Name: (2S,4aR,4bR,6aR,7R,9aR)-4a,6a,12-trimethyl-7-((R)-6-methylheptan-2-yl)-11,13-dioxo-2,3,4,4a,4b,5,6,6a,7,8,9,9a,12,13-tetradecahydro-1H,11H-9b,14a-ethenobenzo[c]cyclopenta[h][1,2,4]triazolo[1,2-a]cinnolin-2-yl 2-bromoacetate
InChIKey: LBFDLJSQMPCWKK-YMNKQYQVSA-N
SMILES: O=C1N2C34[C@@](CC[C@]5([C@@]4([H])CC[C@]5([H])[C@H](C)CCCC(C)C)C)([H])[C@@]6(C(C=C3)(C[C@H](CC6)OC(CBr)=O)N2C(N1C)=O)C
Biological Activity: MeTC7 is a Vitamin-D receptor (VDR) antagonist. MeTC7 has potent VDR inhibition activity with an IC50 value of 2.9 μM. MeTC7 shows good antitumor effects[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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MeTC7 | 99.88% | MeTC7 is a Vitamin-D receptor (VDR) antagonist. MeTC7 has potent VDR inhibition activity with an IC50 value of 2.9 μM. MeTC7 shows good antitumor effects. | ||||||||||||||||||||
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Cholesteryl acetate | 99.21% | Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester that is exported from Saccharomyces cerevisiae via a Pry1-dependent mechanism. Cholesteryl acetate binds to the CAP superfamily protein Pry1 via interactions dependent on Pry1’s caveolin-binding motif. | ||||||||||||||||||||
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Impurity C of Calcitriol | 99.84% | Impurity C of Calcitriol is the impurity of Calcitriol (HY-10002). Calcitriol is the hormonally active form of vitamin D. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). | ||||||||||||||||||||
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Impurity C of Alfacalcidol | 99.81% | Alfacalcidol Impurity C is a diol compound and an impurity of Alfacalcidol (HY-10003). | ||||||||||||||||||||
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oxLig-1 | oxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) is the lipid moiety of oxidized low-density lipoprotein (oxLDL) and is a key ligand for β-glycoprotein I (β(2)-GPI). oxLig-1 causes nuclear translocation by activating the NF-κB pathway. oxLig-1 can be used in the study of atherosclerosis (AS). | |||||||||||||||||||||
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Cholesteryl isovalerate | Cholesteryl isovalerate is an ester product. | |||||||||||||||||||||
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Cholesteryl γ-aminobutyrate | Cholesteryl γ-aminobutyrate is a γ-aminobutyric acid (GABA)-mimetic prodrug. Cholesteryl γ-aminobutyrate inhibits the orthodromically-evoked discharge of pyramidal cells in the CA1 region of the hippocampus. Cholesteryl γ-aminobutyrate suppresses the open-field activity of mice and rats in a dose-dependent manner and inhibits Bicuculline (HY-N0219)-induced seizures in mice. Cholesteryl γ-aminobutyrate can be used for the study of CNS diseases related to impaired GABAergic neuronal function. | |||||||||||||||||||||
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Cholesteryl hemisuccinate | 99.94% | Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth. | ||||||||||||||||||||
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Cholesteryl n-butyrate | 99.97% | Cholesteryl n-butyrate is a cholesterol ester composed of cholesterol and butyrate, two naturally occurring substances. Cholesteryl n-butyrate can be used to synthesize solid lipid nanoparticles (SLNs) with inhibitory activity on the adhesion and migration of colon cancer cells, providing a delivery system for the anticancer drug butyrate. | ||||||||||||||||||||
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Cholesteryl propionate | Cholesteryl propionate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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Cholesteryl n-valerate | Cholesteryl n-valerate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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