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Cat. No.: HY-182449

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CCT365386

CCT365386 is a BCL6 inhibitor. CCT365386 serves as an optimized lead compound for cell-active BCL6 degraders (including CCT369260 (HY-129188)). CCT365386 can be used in the research of B-cell lymphoma.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2647503-59-9
Formule: C₁₅H₁₂ClN₅O
Masse moléculaire:313.74

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CCT365386 Chemical Structure

CAS No.: 2647503-59-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Bcl-2 Family :

In Vitro

CCT365386 (Compound 1) inhibits the interaction between the BCL6 BTB domain and corepressor peptides in TR-FRET biochemical assays, with an IC₅₀ of 3.27 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2647503-59-9
Masse moléculaire 313.74
Formule C₁₅H₁₂ClN₅O
SMILES

N#CC1=C(NC2=CC=C3C(N(C)C(N3C)=O)=C2)C=CN=C1Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Lloyd MG, et al. Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket. J Med Chem. 2021;64(23):17079-17097. [Content Brief]

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Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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- In Vitro
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CCT365386

Voir tous les produits spécifiques à Isoform Bcl-2 Family

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CCT365386 Related Classifications

HY-182449 Related Classifications