DAB-1
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- CAS No.: 100937-52-8
- Formule: C5H11NO3
- Masse moléculaire:133.15
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
1 μM
Compound: 1, D-AB1
|
Inhibition of glucagon-stimulated glycogenolysis in Wistar rat hepatocytes assessed as glucose release after 90 mins
Inhibition of glucagon-stimulated glycogenolysis in Wistar rat hepatocytes assessed as glucose release after 90 mins
|
[PMID: 18258441] |
| Hepatocyte | IC50 |
1 μM
Compound: D-AB1
|
Inhibition of basal glycogenolysis in rat primary hepatocytes
Inhibition of basal glycogenolysis in rat primary hepatocytes
|
[PMID: 18595718] |
| Hepatocyte | IC50 |
1 μM
Compound: M1, DAB
|
Inhibition of glycogen phosphorylase in rat hepatocytes assessed as reduction in basal glycogenolysis
Inhibition of glycogen phosphorylase in rat hepatocytes assessed as reduction in basal glycogenolysis
|
[PMID: 23378626] |
| Hepatocyte | IC50 |
1.1 μM
Compound: M1, DAB
|
Inhibition of glycogen phosphorylase in rat hepatocytes assessed as reduction in glucagom-induced glycogenolysis
Inhibition of glycogen phosphorylase in rat hepatocytes assessed as reduction in glucagom-induced glycogenolysis
|
[PMID: 23378626] |
| Hepatocyte | IC50 |
9 μM
Compound: D-AB1
|
Inhibition of glucagon-induced glucose production in rat primary hepatocytes
Inhibition of glucagon-induced glucose production in rat primary hepatocytes
|
[PMID: 18595718] |
| MOLT-4 | CC50 |
>100 mg/mL
Compound: 4
|
Concentration giving 50% inhibition of growth of mock-infected MOLT-4 cells
Concentration giving 50% inhibition of growth of mock-infected MOLT-4 cells
|
[PMID: 7608901] |
| MOLT-4 | EC50 |
>100 mg/mL
Compound: 4
|
Concentration giving 50% inhibition of HIV-1 induced cytopathogenicity in MOLT-4 cells
Concentration giving 50% inhibition of HIV-1 induced cytopathogenicity in MOLT-4 cells
|
[PMID: 7608901] |
| MT4 | CC50 |
>100 mg/mL
Compound: 4
|
Concentration giving 50% inhibition of growth of mock-infected MT-4 cells
Concentration giving 50% inhibition of growth of mock-infected MT-4 cells
|
[PMID: 7608901] |
| MT4 | EC50 |
>100 mg/mL
Compound: 4
|
Concentration giving 50% inhibition of HIV-1 induced cytopathogenicity in MT-4 cells
Concentration giving 50% inhibition of HIV-1 induced cytopathogenicity in MT-4 cells
|
[PMID: 7608901] |
Chemical Information
-
CAS No. 100937-52-8
-
Masse moléculaire 133.15
-
Formule C5H11NO3
-
SMILES
C(O)[C@@H]1[C@@H](O)[C@H](O)CN1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)