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Cat. No.: HY-115836

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DDPO

DDPO is an inhibitor for dihydrofolate reductase (DHFR) with an IC₅₀ of 0.035 µM. DDPO inhibits the cell growth of cancer cell L1210 and WI-L2with IC₅₀ of 5 and 0.28 µM.

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CAS No.: 118675-83-5
Formule: C₂₁H₂₄N₆O₄
Masse moléculaire:424.45

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

DDPO Chemical Structure

CAS No.: 118675-83-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

DDPO is an inhibitor for dihydrofolate reductase (DHFR) with an IC₅₀ of 0.035 µM. DDPO inhibits the cell growth of cancer cell L1210 and WI-L2with IC₅₀ of 5 and 0.28 µM^[1].

Chemical Information

CAS No. 118675-83-5
Masse moléculaire 424.45
Formule C₂₁H₂₄N₆O₄
SMILES

O=C1C2=CC(CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCCN)=O)=CC=C2NC(N)=N1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Rosowsky A, et al., Synthesis and in vitro biological activity of new deaza analogues of folic acid, aminopterin, and methotrexate with an L-ornithine side chain.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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