DN-108
DN-108, a thiazolidinedione derivative, is an orally active peroxisome proliferator-activated receptor γ (PPARγ) agonist with antidiabetic effects. DN-108 improves hyperglycemia, hypertriglyceridemia and hyperinsulinemia in diabetic mouse models. DN-108 enhances tissue glucose uptake (e.g., increasing 2-deoxyglucose uptake in L6 muscle cells) and inhibits fatty acid synthase activity. DN-108 is promising for research of type 2 diabetes.
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- CAS No.: 195604-21-8
- Formule: C20H18N2O3S
- Masse moléculaire:366.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
IC50 & Target
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PPARγ |
Chemical Information
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CAS No. 195604-21-8
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Masse moléculaire 366.43
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Formule C20H18N2O3S
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SMILES
O=C1SC(CC2=CC=C(NC(C3(CC3)C4=CC=CC=C4)=O)C=C2)C(N1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DN-108 Related Classifications
HY-171793 Related Classifications
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