DS-1040
DS-1040 is a low-molecular-weight imidazole derivative. DS-1040 is an inhibitor of the activated thrombin-activatable fibrinolysis (TAFIa). DS-1040 can promote fibrinolysis through suppressing TAFIa activity. DS-1040 can be studied in thrombolytic disease research.
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- CAS No.: 1335138-62-9
- Formule: C16H27N3O2
- Masse moléculaire:293.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 1335138-62-9
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Masse moléculaire 293.40
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Formule C16H27N3O2
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SMILES
C[C@H]1CC[C@H](N2C=NC(C[C@@H](C(O)=O)CCCN)=C2)CC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Zhou, J., et al., (2017). A first-in-human study of DS-1040, an inhibitor of the activated form of thrombin-activatable fibrinolysis inhibitor, in healthy subjects. Journal of thrombosis and haemostasis : JTH, 15(5), 961-971. [Content Brief]
[2]. Zhou, J., et al., (2019). First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of an Oral Formulation of DS-1040, an Inhibitor of the Activated Form of Thrombin-Activatable Fibrinolysis Inhibitor, in Healthy Subjects. Journal of clinical pharmacology, 59(12), 1669-1677. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DS-1040 Related Classifications
HY-117745 Related Classifications
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