DS42450411
DS42450411 is an orally active hepcidin production inhibitor with an IC50 of 32 nM. DS42450411 in an acute inflammatory mouse model induced by IL-6, DS42450411 significantly reduces serum hepcidin levels. DS42450411 can be used for studying iron homeostasis.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2247168-13-2
- Formule: C22H28N4
- Masse moléculaire:348.48
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
0.032 μM
Compound: 34; DS42450411
|
Inhibition of BMP6-stimulated hepcidin production in human HepG2 cells
Inhibition of BMP6-stimulated hepcidin production in human HepG2 cells
|
[PMID: 30217414] |
Chemical Information
-
CAS No. 2247168-13-2
-
Masse moléculaire 348.48
-
Formule C22H28N4
-
SMILES
NC1=C2C(C)(C)CC3=CC(C([C@H]4CC[C@H](N)CC4)=C)=CC=C3C2=NC=N1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DS42450411 Related Classifications
HY-125288 Related Classifications
Powered by Bioz