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Cat. No.: HY-105128

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Epostane

(Synonyms: WIN 32729)

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Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC₅₀ of 1.45 nM. Epostane blocks ovulation and pregnancy in rats.

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Pureté: 99.0%
CAS No.: 80471-63-2
Formule: C₂₂H₃₁NO₃
Masse moléculaire:357.49

Stockage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Epostane Chemical Structure

CAS No.: 80471-63-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC₅₀ of 1.45 nM. Epostane blocks ovulation and pregnancy in rats^[1].

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3β-HSD I

In Vivo

Epostane (0-200 mg/kg, p.o., single dose) inhibits ovulation in mature rats and gonadotropin-stimulated ovulation in immature rats, terminates pregnancy through lowering plasma progesterone levels^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Sprague Dawley rats model^[1]
Dosage:

0-200 mg/kg
Administration:

p.o., single dose
Result:

Terminated ovulation and pregnancy in rats, which was reversed by injections of progesterone.

Chemical Information

CAS No. 80471-63-2
Appearance Solid
Masse moléculaire 357.49
Formule C₂₂H₃₁NO₃
Color White to off-white
SMILES

C[C@@]12[C@@]3(CC[C@]4([H])[C@]2([H])CC[C@]5([C@@]4([H])CC[C@@]5(O)C)C)[C@](O3)(C(O)=C(C1)C#N)C
Synonyms

WIN 32729
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Snyder BW, et al., Inhibition of ovulation in rats with epostane, an inhibitor of 3 beta-hydroxysteroid dehydrogenase. Proc Soc Exp Biol Med. 1984 Jul;176(3):238-42. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références

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Epostane

Voir tous les produits spécifiques à Isoform 3β-HSD

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Epostane Related Classifications

HY-105128 Related Classifications