Estradiol acetate
Estradiol acetate is a novel orally active Estradiol (HY-B0141) prodrug. Estradiol acetate reduces the frequency and severity of postmenopause symptoms. Estradiol acetate can be used in the research of menopausal symptoms.
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- CAS No.: 4245-41-4
- Formule: C20H26O3
- Masse moléculaire:314.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | Inhibition |
101.033 %
Compound: ESTRADIOL ACETATE
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Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
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[PMID: 23571415] |
| CHO | Inhibition |
456.299 %
Compound: ESTRADIOL ACETATE
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Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
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[PMID: 23571415] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 4245-41-4
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Masse moléculaire 314.42
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Formule C20H26O3
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SMILES
C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OC(C)=O)C=C4CC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Utian WH, et al. Comparative controlled trial of a novel oral estrogen therapy, estradiol acetate, for relief of menopause symptoms. Menopause. 2005 Nov-Dec;12(6):708-15. [Content Brief]
[2]. Speroff L, et al. Efficacy of a new, oral estradiol acetate formulation for relief of menopause symptoms. Menopause. 2006 May-Jun;13(3):442-50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Estradiol acetate Related Classifications
HY-B0709 Related Classifications
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