GCC-1
GCC-1 is a glycolipid. GCC-1 binds to CD1d to form a glycolipid-CD1d complex, which is presented to cellular TCR, thereby activating cells in a CD1d-dependent manner. GCC-1 induces Th1-biased cellular activation and IFN-γ production. GCC-1 can be used for research on colon adenocarcinoma.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C52H93NO10
- Masse moléculaire:892.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
CD1d |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c mice[1]
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Dosage:1 nmol
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Administration:i.v.; on days 3 and 10
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Result:Reduced average tumor volume to approximately 1000 mm3 on day 30, whereas control groups exhibited tumor volumes close to 2000 mm3.
Significantly prolonged survival relative to αGalCer.
Chemical Information
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Masse moléculaire 892.30
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Formule C52H93NO10
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SMILES
OC[C@H]([C@@H]([C@@H]([C@H]1O)O)O)O[C@@H]1OC[C@H](NC(CC2=CC=C(OCC3CCCCCCCCCCCCCCCCCC3)C=C2)=O)[C@H](O)[C@@H](CCCCCCCCCCCCCC)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GCC-1 Related Classifications
HY-189458 Related Classifications
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