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Cat. No.: HY-P10321

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HBP08

HBP08 is a selective inhibitor of CXCL12/HMGB1 interaction. HBP08 has a high affinity for HMGB1 (K_d=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration.

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CAS No.: 2490442-13-0
Formule: C₆₀H₇₇N₁₇O₁₄
Masse moléculaire:1260.36

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Please store the product under the recommended conditions in the Certificate of Analysis.

HBP08 Chemical Structure

CAS No.: 2490442-13-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

HBP08 is a selective inhibitor of CXCL12/HMGB1 interaction. HBP08 has a high affinity for HMGB1 (K_d=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration^[1].

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Chemical Information

CAS No. 2490442-13-0
Masse moléculaire 1260.36
Formule C₆₀H₇₇N₁₇O₁₄
Sequence

Gly-Tyr-His-Tyr-Glu-Arg-Trp-Ile-His
Sequence Shortening

GYHYERWIH
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sgrignani J, et al. Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction. J Med Chem. 2021 Sep 23;64(18):13439-13450. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
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HBP08

Voir tous les produits spécifiques à Isoform CXCR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

HBP08 Related Classifications

HY-P10321 Related Classifications