HET0016 (Standard)
HET0016 (Standard) is the analytical standard of HET0016. This product is intended for research and analytical applications. HET0016 is a potent and selective 20-hydroxyeicosatetraenoic acid (20-HETE) synthase inhibitor, with IC50 values of 17.7 nM, 12.1 nM and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth.
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- Pureté: 98%
- CAS No.: 339068-25-6
- Formule: C12H18N2O
- Masse moléculaire:206.28
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-124527
HET0016
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HY-B1311
Proadifen hydrochloride
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HY-13215
Avasimibe
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HY-75054
Abiraterone acetate
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HY-19340
TMS
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HY-N2229
Rhapontigenin
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HY-B0873
Uniconazole
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HY-70006
Galeterone
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HY-75054R
Abiraterone acetate (Standard)
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HY-B1311R
Proadifen hydrochloride (Standard)
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HY-13215R
Avasimibe (Standard)
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HY-B0873R
Uniconazole (Standard)
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 339068-25-6
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Masse moléculaire 206.28
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Formule C12H18N2O
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SMILES
CCCCC1=CC=C(C(C)=C1)/N=C/NO
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Seki T, et al. Cytochrome P450 4A isoform inhibitory profile of N-hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine (HET0016), a selective inhibitor of 20-HETE synthesis. Biol Pharm Bull. 2005 Sep;28(9):1651-4. [Content Brief]
[2]. Borin TF, et al. HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model. PLoS One. 2017 Jun 13;12(6):e0178830. [Content Brief]
[3]. Liu Y, et al. The protective effect of HET0016 on brain edema and blood-brain barrier dysfunction after cerebral ischemia/reperfusion. Brain Res. 2014 Jan 28;1544:45-53. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HET0016 (Standard) Related Classifications
HY-124527R Related Classifications
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