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Cat. No.: HY-159985

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Jun13728

Jun13728 is a potent and covalent SARS-CoV-2 papain-like protease inhibitor, with an IC₅₀ of 0.1 μM. Jun13728 can be used for SARS-CoV-2 antiviral research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₃₄H₃₆F₂N₈O₄
Masse moléculaire:658.70

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Jun13728 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Jun13728 is a potent and covalent SARS-CoV-2 papain-like protease inhibitor, with an IC₅₀ of 0.1 μM. Jun13728 can be used for SARS-CoV-2 antiviral research^[1].

Chemical Information

Masse moléculaire 658.70
Formule C₃₄H₃₆F₂N₈O₄
SMILES

O=C(N[C@@H](C1=CC(C2=CN(N=C2)C)=CC(C3=NN(C=C3)CC)=C1)C)C4=CC=CC=C4CCC(NNC(/C=C/C(N5CC(F)(C5)F)=O)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Tan B, et, al. Structure-Based Design of Covalent SARS-CoV-2 Papain-like Protease Inhibitors. J Med Chem. 2024 Nov 28;67(22):20399-20420. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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