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Cat. No.: HY-N5126

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Juncusol

Name: Juncusol
Brand: MedChemExpress
SKU: HY-N5126
Price: 220.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Juncusol, a phenanthrenoid found in Juncus setchuenensis, possesses anxiolytic effect. Juncusol is associated with metabolic changes in cortical serotonin/dopamine levels in Mice.

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CAS No.: 62023-90-9
Formule: C₁₈H₁₈O₂
Masse moléculaire:266.33

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Juncusol Chemical Structure

CAS No.: 62023-90-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
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Activité biologique

Description

Juncusol, a phenanthrenoid found in Juncus setchuenensis, possesses anxiolytic effect. Juncusol is associated with metabolic changes in cortical serotonin/dopamine levels in Mice^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
B16	IC₅₀	12.5 μg/mL Compound: 1a	In vitro cytotoxic activity against B-16 mouse melanoma (B-16) In vitro cytotoxic activity against B-16 mouse melanoma (B-16)	[PMID: 4045930]
HEK293	IC₅₀	6.5 μM Compound: 8	Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay	[PMID: 30892891]
L1210	IC₅₀	13.8 μg/mL Compound: 1a	In vitro cytotoxic activity against L-1210 mouse lymphocytic leukemia cell culture (ATCC CCL-219) In vitro cytotoxic activity against L-1210 mouse lymphocytic leukemia cell culture (ATCC CCL-219)	[PMID: 4045930]
RAW264.7	IC₅₀	3.1 μM Compound: Juncusol	Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 48 hrs by Griess reagent assay Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 48 hrs by Griess reagent assay	[PMID: 29280630]

Chemical Information

CAS No. 62023-90-9
Masse moléculaire 266.33
Formule C₁₈H₁₈O₂
SMILES

OC(C(C)=C1CC2)=CC=C1C3=C2C=C(O)C(C)=C3C=C
Structure Classification
- Phenols
- Polyphenols
- Others
Initial Source
- Plants
- other families
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lu Sun, et al. Anxiolytic effect of a novel 9,10-dihydrophenanthrene, juncuenin H, is associated with metabolic changes in cortical serotonin/dopamine levels in mice. Fitoterapia. 2019 Apr;134:165-171. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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