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Cat. No.: HY-100843

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L-AP6

L-AP6 is a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons.

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CAS No.: 78944-89-5
Formule: C₆H₁₄NO₅P
Masse moléculaire:211.15

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

L-AP6 Chemical Structure

CAS No.: 78944-89-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

L-AP6 is a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Pyramidal neuron	IC₅₀	0.17 μM Compound: L-AP6	sensitization of CA1 pyramidal neurons to depolarizations by L-AP6 after exposure to quisqualic acid sensitization of CA1 pyramidal neurons to depolarizations by L-AP6 after exposure to quisqualic acid	[PMID: 7966155]
Pyramidal neuron	IC₅₀	11 μM Compound: L-AP6	sensitization of CA1 pyramidal neurons by 2 to depolarizations by L-AP4, L-AP5 and L-AP6 before exposure to quisqualic acid sensitization of CA1 pyramidal neurons by 2 to depolarizations by L-AP4, L-AP5 and L-AP6 before exposure to quisqualic acid	[PMID: 7966155]
Pyramidal neuron	IC₅₀	12 μM Compound: L-AP6	sensitization of CA1 pyramidal neurons by 2 to depolarizations by L-AP4, L-AP5 and L-AP6 after reversal with L-alpha-AA sensitization of CA1 pyramidal neurons by 2 to depolarizations by L-AP4, L-AP5 and L-AP6 after reversal with L-alpha-AA	[PMID: 7966155]

Chemical Information

CAS No. 78944-89-5
Masse moléculaire 211.15
Formule C₆H₁₄NO₅P
SMILES

NC(CCCCP(O)(O)=O)C(O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Schulte MK, et, al. Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons. Brain Res. 1994 Jun 27;649(1-2):203-7. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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L-AP6

High-Throughput Bioactive Compound Library

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