Matricarin
Matricarin is a sesquiterpene lactone antioxidant with ferric ion reducing antioxidant power activity. Matricarin exhibits free radical scavenging activity. Matricarin induces growth inhibition. Matricarin can be used in the research of ovarian cancer and renal cancer.
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- CAS No.: 5989-43-5
- Formule: C17H20O5
- Masse moléculaire:304.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
100 μM
Compound: 8
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess reagent based spectrophotometric analysis
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess reagent based spectrophotometric analysis
|
[PMID: 29122483] |
In Vitro
Matricarin is a compound isolated from the leaves of the Artemisia tridentata tridentata subspecies, and its ferric reducing antioxidant activity is 13.22 µM TE/g FW[1].
Matricarin (10-5 M) achieves a growth inhibition rate of up to 89% in OVCAR-3 ovarian cancer cells and a lethality rate of 28% in A498 renal cancer cells, but its overall anti-tumor activity in the NCI-60 cell panel is not significant[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 5989-43-5
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Masse moléculaire 304.34
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Formule C17H20O5
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SMILES
CC([C@]1([H])[C@]2([H])[C@@]([C@@H](C(O2)=O)C)([H])[C@H](CC(C)=C13)OC(C)=O)=CC3=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Matricarin
- 5989-43-5
- Biochemical Assay Reagents
- radical-scavenging capacity
- OVCAR-3 ovarian cancer cells
- antioxidant
- ferric reducing antioxidant power
- A498 renal cancer cells
- Artemisia tridentata subsp. tridentata
- renal cancer
- ovarian cancer
- NCI-60 cancer cell line
- sesquiterpene lactone
- Inhibitor
- inhibitor
- inhibit