PEG600
Based on 1 Customer Validation
PEG600 can be used as an excipient, such as ointment base, lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
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- Pureté: 98.0%
- CAS No.: 25322-68-3
- Masse moléculaire:600.00
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Activité biologique
The FDA has approved polyethylene glycol (PEG) for use as a vehicle or base in foods, cosmetics and pharmaceuticals, including injectable, topical, rectal and nasal formulations. PEG shows little toxicity, and is eliminated from the body intact by either the kidneys (for PEGs < 30 kDa) or in the faeces (for PEGs > 20 kDa). PEG lacks immunogenicity, and antibodies to PEG are generated in rabbits only if PEG is combined with highly immunogenic proteins[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 25322-68-3
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Appearance <18°C Solid, >22°C Liquid
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Masse moléculaire 600.00
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Color Colorless to off-white
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SMILES
[H]OCCO[H].[n]
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Synonyms
Polyethylene glycol 600
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
DMSO : 200 mg/mL (333.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 175 mg/mL (291.67 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 1.6667 mL | 8.3333 mL | 16.6667 mL | 41.6667 mL |
| 5 mM | 0.3333 mL | 1.6667 mL | 3.3333 mL | 8.3333 mL | |
| 10 mM | 0.1667 mL | 0.8333 mL | 1.6667 mL | 4.1667 mL | |
| 15 mM | 0.1111 mL | 0.5556 mL | 1.1111 mL | 2.7778 mL | |
| 20 mM | 0.0833 mL | 0.4167 mL | 0.8333 mL | 2.0833 mL | |
| 25 mM | 0.0667 mL | 0.3333 mL | 0.6667 mL | 1.6667 mL | |
| 30 mM | 0.0556 mL | 0.2778 mL | 0.5556 mL | 1.3889 mL | |
| 40 mM | 0.0417 mL | 0.2083 mL | 0.4167 mL | 1.0417 mL | |
| 50 mM | 0.0333 mL | 0.1667 mL | 0.3333 mL | 0.8333 mL | |
| 60 mM | 0.0278 mL | 0.1389 mL | 0.2778 mL | 0.6944 mL | |
| 80 mM | 0.0208 mL | 0.1042 mL | 0.2083 mL | 0.5208 mL | |
| 100 mM | 0.0167 mL | 0.0833 mL | 0.1667 mL | 0.4167 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
- PEG600
- 25322-68-3
- Polyethylene glycol 600
- PEG 600
- PEG-600
- Polyethylene glycol600
- Polyethylene glycol-600
- Environmental Pollutants
- Biochemical Assay Reagents
- pharmaceutical excipient
- pharmaceutical auxiliarie
- pharmaceutical ingredients
- inactive ingredients
- stability
- solubility
- processability
- absorption
- distribution
- metabolism
- and elimination (ADME)
- Inhibitor
- inhibitor
- inhibit