SG-210
SG-210 (SPR 210) is an orally active and selective aldose reductase (AR) inhibitor. SG-210 has IC50 values of 9.5 nM and 10 nM for AR from porcine lens and human placenta, respectively. SG-210 can inhibit sorbitol accumulation and ameliorate diabetic neuropathy and retinopathy in Streptozotocin (HY-13753)-induced diabetic rats. SG-210 can be used in the research of diseases such as diabetes-related complications.
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- CAS No.: 143162-65-6
- Formule: C18H11F3N2O3S2
- Masse moléculaire:424.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 143162-65-6
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Masse moléculaire 424.42
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Formule C18H11F3N2O3S2
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SMILES
O=C1N(CC2=NC3=C(S2)C(F)=CC(F)=C3F)C4=CC=CC=C4SC1CC(O)=O
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Synonyms
SPR 210
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SG-210 Related Classifications
HY-106915 Related Classifications
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