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Cat. No.: HY-B0960S

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Sulfabenzamide-d₄

(Synonyms: N-Sulfanilylbenzamide-d₄)

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Sulfabenzamide (N-Sulfanilylbenzamide)-d₄ is the deuterium labeled Sulfabenzamide (HY-B0960). Sulfabenzamide is a sulfonamide antibacterial agent. Sulfabenzamide exhibit antibacterial activity against Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 8739). Sulfabenzamide can promote autophagic cell autophagy in breast cancer cells through p53/ DRAM pathway. Sulfabenzamide increases caspase-3 activity, deactivates PARP1 and DNA-PK, downregulates AKT1 and AKT2. Sulfabenzamide can be used for the researches of breast cancer and bacterial infections.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 99.74%
CAS No.: 2732981-22-3
Formule: C₁₃H₈D₄N₂O₃S
Masse moléculaire:280.34

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Sulfabenzamide-d₄ Chemical Structure

CAS No.: 2732981-22-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- Application
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Caspase :

Voir tous les produits spécifiques à Isoform PARP :

Voir tous les produits spécifiques à Isoform Akt :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 2732981-22-3
Unlabeled Cas 127-71-9
Appearance Solid
Masse moléculaire 280.34
Formule C₁₃H₈D₄N₂O₃S
Color White to off-white
SMILES

O=C(NS(=O)(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])=O)C2=CC=CC=C2
Synonyms

N-Sulfanilylbenzamide-d₄
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mohammadpour R, Safarian S, Farahnak S, et al. Sulfabenzamide promotes autophagic cell death in T-47D breast cancer cells through p53/DRAM pathway[J]. J Cell Mol Biol, 2012, 10(1): 41-54.

[2]. Rostamizadeh S, et al. Synthesis of sulfamethoxazole and sulfabenzamide metal complexes; evaluation of their antibacterial activity. Eur J Med Chem. 2019;171:364-371. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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Sulfabenzamide-d4

Voir tous les produits spécifiques à Isoform Caspase

Voir tous les produits spécifiques à Isoform PARP

Voir tous les produits spécifiques à Isoform Akt

Activité biologique

Chemical Information

Pureté et documentation

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Sulfabenzamide-d4 Related Classifications

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Sulfabenzamide-d₄

Sulfabenzamide-d₄ Related Classifications