Zoxamide
Based on 1 Customer Validation
Zoxamide (RH-7281) is an oomycete Fungicide and covalent β-tubulin inhibitor. RH-7281 inhibits the assembly of tubulin into microtubules in vitro. Zoxamide binds covalently to β-tubulin, disrupting microtubule assembly and the cytoskeleton. Zoxamide blocks nuclear division in germinated hyphae of Phytophthora capsici and inhibits hyphal growth of Phytophthora capsici.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.05%
- CAS No.: 156052-68-5
- Formule: C14H16Cl3NO2
- Masse moléculaire:336.64
-
Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
-
Anti-Infection Compound Library
HY-L002
-
Cell Cycle/DNA Damage Compound Library
HY-L004
-
Anti-Aging Compound Library
HY-L034
-
Antifungal Compound Library
HY-L048
-
Cytoskeleton Compound Library
HY-L060
-
Anti-Lung Cancer Compound Library
HY-L075
-
Protein-protein Interaction Inhibitor Library
HY-L109
-
Cysteine Targeted Covalent Library
HY-L153
-
Multi-Target Compound Library
HY-L176
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
Pesticide Compound Library
HY-L183
-
High-Throughput Bioactive Compound Library
HY-L205
-
High-Efficiency Gene Editing Compound Library
HY-L244
Activité biologique
Studies show that all field-collected isolates of Phytophthora cactorum are sensitive to zoxamide (0.02-1.0 mg/L; 6 days), with a mean EC50 value of 0.14 mg/L for inhibiting radial mycelial growth[1].
Zoxamide (0-1 ppm) rapidly and potently inhibits nuclear division in Phytophthora capsici seedlings[2].
Zoxamide (0.05 ppm; 30 min) completely disrupts the microtubule cytoskeleton in germ tubes of *Phytophthora capsici*, eliminating detectable microtubule filaments[2].
Zoxamide (5-30 μM; 1-8 h) inhibits in vitro microtubule assembly of tubulin isolated from bovine brain in a dose-dependent manner, and its inhibitory potency increases with prolonged pre-incubation time[2].
Zoxamide (16 h) potently inhibits the mycelial growth of *Phytophthora capsici* in microtiter plate assays, with an EC50 of 0.0031 ppm[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 156052-68-5
-
Appearance Solid
-
Masse moléculaire 336.64
-
Formule C14H16Cl3NO2
-
Color White to off-white
-
SMILES
O=C(NC(C)(CC)C(CCl)=O)C1=CC(Cl)=C(C)C(Cl)=C1
-
Synonyms
RH-7281
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
-
Fiche technique (267 KB)
-
SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
-
Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Zoxamide Related Classifications
HY-120921 Related Classifications
Powered by Bioz